Jen Pfleghaar has built her medical practice around a part of women's health that's often misunderstood: the hormonal shifts that happen across the menstrual cycle and into perimenopause. She joined Sean Kelly on the Digital Social Hour at the A4M conference to break down cycle syncing and what it actually means for women's health.
The conversation moves through training, fertility, and stress, with Jen Pfleghaar walking through her own clinical perspective on why so many women are told to push through symptoms that hormones may actually be causing.
About Jen Pfleghaar
Jen Pfleghaar is an integrative physician focused on women's hormone health, including cycle syncing and perimenopause. She is the author of The Perimenopause Reset, and her work centers on helping women understand how hormonal phases affect training, mood, and overall wellness.
Her approach draws on integrative medicine, looking beyond standard prescriptions to address the role of stress, insulin resistance, and endocrine disruptors in women's hormone health. She has spoken at conferences like A4M, sharing her clinical perspective on perimenopause with both patients and peers.
What Jen Pfleghaar and Sean Kelly Talked About
- Her explanation of cycle syncing and why hormone phases affect how women should train
- Her view on how intense workouts like HIIT and marathon training can spike cortisol in perimenopause
- Why she connects insulin resistance and PCOS to fertility and cycle irregularities
- Her perspective on how endocrine disruptors like plastics may affect hormone balance
- How she reframes low libido as often tied to stress and cortisol rather than testosterone alone
- Her take on how understanding cycle phases can improve communication in relationships
- Why she highlights pelvic floor therapy as an overlooked tool for recovery and comfort
- Her approach to hormone health that looks beyond standard prescriptions
Why This Conversation Matters
Women's hormone health is a topic that rarely gets this kind of clear, clinical treatment. Jen Pfleghaar's conversation with Sean Kelly translates cycle syncing and perimenopause into practical language, drawn from her own integrative medicine background.
▶ Watch the full episode on YouTube
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About Sean Kelly & the Digital Social Hour
Sean Kelly is an entrepreneur and the host of the Digital Social Hour, one of the fastest-growing interview podcasts in the world, where he sits down with entrepreneurs, athletes, creators, and cultural voices for candid, long-form conversations. The show draws over 100 million views a month across platforms. Explore more guest features on SeanKelly.io.
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